# Appendix: Principles of Cellular Interaction

The design for the MAP has been patterned after that of living systems. A key source of inspiration was Diane Tegtmeier's book: [Relationships that Heal: Skillful Practice within Nature's Web](http://dianetegtmeier.com/book-reviews_290.html). This book beautifully describes how Ms. Tegtmeier discovered how the principles of cellular interaction she learned during her initial education as a microbiologist could be effectively applied to healing human relationships. It not only offers a distillation of six key principles (illustrated in the following diagram), but demonstrates how they can be fractally applied at entirely different levels of agency.

![Adapted from  Relationships that Heal: Skillful Practice within Nature's Web by Diane Tegtmeier](https://777163467-files.gitbook.io/~/files/v0/b/gitbook-x-prod.appspot.com/o/spaces%2F-Mgr-A9gty1QVUBTbFyp%2Fuploads%2FDT7z6627Jf0CDf71WO5L%2Fimage.png?alt=media\&token=33fc86ff-58c5-413a-9f47-30ab1417b9d8)

***Containment*** -- cells are circumscribed by enclosing membranes that offer a degree of separation from their surrounding environment. Thus, cells have an inside and and outside. This concept of containment can be generalized as a characteristic of all agents. In biological (genetic) organisms, the membrane is physical (e.g., cell wall, skin), whereas in memetic organisms, this membrane is virtual (e.g., the letters of incorporation of a for-profit business establishes a legal "membrane" around its affairs). 

***Selective Permeability*** --

***Interspace*** --

***Differentiation*** --

***Sense & Respond*** --

***Interdependence*** --